BackgroundThe preferable position of Deep Brain Stimulation electrodes is proposed to be located in the dorsolateral subthalamic nucleus to improve general motor performance. The optimal DBS electrode localization for the post-operative improvement of balance and gait is unknown.MethodsIn this single-center, retrospective analyses, 66 Parkinson’s disease patients were assessed pre- and post-operatively by using MDS-UPDRS, freezing of gait score, Giladi’s gait and falls questionnaire and Berg balance scale. The clinical outcome was related to the DBS electrode coordinates in x, y, z (...) plane as revealed by image-based reconstruction. Binomial generalized linear mixed models with fixed-effect variables electrode asymmetry, parkinsonian subtype, medication, age class and clinical DBS induced changes were analyzed.ResultsSubthalamic nucleus-deep brain stimulation improved all motor, balance and FoG scores in MED OFF condition, however there were heterogeneous results in MED ON condition. DBS electrode reconstructed coordinates impacted the responsiveness of axial symptoms. FoG and balance responders showed slightly more medially located STN electrode coordinates and less medio-lateral asymmetry of the electrode reconstructed coordinates across hemispheres compared to non-responders.ConclusionDeep brain stimulation electrode reconstructed coordinates, particularly electrode asymmetry on the medio-lateral axis affected the post-operative responsiveness of balance and FoG symptoms in PD patients. (shrink)

Many types of everyday and specialized reasoning depend on diagrams: we use maps to find our way, we draw graphs and sketches to communicate concepts and prove geometrical theorems, and we manipulate diagrams to explore new creative solutions to problems. The active involvement and manipulation of representational artifacts for purposes of thinking and communicating is discussed in relation to C.S. Peirce’s notion of diagrammatical reasoning. We propose to extend Peirce’s original ideas and sketch a conceptual framework that delineates different kinds (...) of diagram manipulation: Sometimes diagrams are manipulated in order to profile known information in an optimal fashion. At other times diagrams are explored in order to gain new insights, solve problems or discover hidden meaning potentials. The latter cases often entail manipulations that either generate additional information or extract information by means of abstraction. Ideas are substantiated by reference to ethnographic, experimental and historical examples. (shrink)

Compelling evidence is presented that Glauber worked as a laborator (laboratory assistant) for Landgrave Georg of Hesse-Darmstadt from 1632/33 till he was appointed apothecary in Giessen in 1635. During this time, he was also used as laborator by the landgrave’s personal physician, Helwig Dieterich. Glauber became a famous chemist, whose alchemical secrets were keenly solicited by King Frederik III of Denmark, Queen Christina of Sweden, and, according to the 1662 diary of Ole Borch, King Charles II of England. A (...) 1689 letter to Queen Christina contains detailed descriptions of Glauber’s alkahest, his decomposition and redintegration of saltpeter, and his ‘most secret sal armoniacum’, which is interpreted here for the first time. (shrink)

L? Esquisse d?une théorie des émotions est traduite en anglais une première fois en 1948 1 . Elle le sera une seconde fois en 1962. Ces traductions ont suscité de nombreux comptes rendus et ont donné lieu depuis lors à de nombreuses lectures du petit livre de Sartre, alors que l?ouvrage a longtemps été négligé par les travaux de langue française 2 . En 1950, deux articles de grande qualité scellent cet intérêt anglo-saxon pour l??uvre de Sartre en général, et (...) pour l? Esquisse d?une théorie des émotions en particulier, dans cette période d?immédiat après-guerre. Le premier est écrit par Günther Stern, le second par Frederik Jacobus Johannes Buytendijk 3 . Ils adressent des questions fondamentales au livre de Sartre, à propos du rapport de l?émotion à la réalité d?une part, du rapport de l?émotion au langage de l?autre. L?émo­tion chez Sartre semble en effet se définir comme une façon de fuir la réalité, devenue trop difficile . C?est ce que semble indiquer la définition de l?émo­tion comme conscience magique. L?émotion serait ainsi, pour Sartre, la manière dont la conscience tenue en échec, mise en impasse, prétend agir directement, sans médiation, sur le monde. Dans le cadre de cet article, je me limiterai à une discussion du premier article, qui adressait déjà, sans que les commentaires suivants aient pu égaler son acuité, les questions fondamentales. Dans un premier temps, je rappellerai de. (shrink)

This book is the first to trace the origins and significance of positivism on a global scale. Taking their cues from Auguste Comte and John Stuart Mill, positivists pioneered a universal, experience-based culture of scientific inquiry for studying nature and society—a new science that would enlighten all of humankind. Positivists envisaged one world united by science, but their efforts spawned many. Uncovering these worlds of positivism, the volume ranges from India, the Ottoman Empire, and the Iberian Peninsula to Central Europe, (...) Russia, and Brazil, examining positivism’s impact as one of the most far-reaching intellectual movements of the modern world. Positivists reinvented science, claiming it to be distinct from and superior to the humanities. They predicated political governance on their refashioned science of society, and as political activists, they sought and often failed to reconcile their universalism with the values of multiculturalism. Providing a genealogy of scientific governance that is sorely needed in an age of post-truth politics, this volume breaks new ground in the fields of intellectual and global history, the history of science, and philosophy. (shrink)

In this volume, the author investigates and argues for, a particular answer to the question: What is the right way to logically analyze modalities from natural language within formal languages? The answer is: by formalizing modal expressions in terms of predicates. But, as in the case of truth, the most intuitive modal principles lead to paradox once the modal notions are conceived as predicates. -/- The book discusses the philosophical interpretation of these modal paradoxes and argues that any satisfactory approach (...) to modality will have to face the paradoxes independently of the grammatical category of the modal notion. By systematizing modal principles with respect to their joint consistency and inconsistency, Stern provides an overview of the options and limitations of the predicate approach to modality that may serve as a useful starting point for future work on predicate approaches to modality. Stern also develops a general strategy for constructing philosophically attractive theories of modal notions conceived as predicates. The idea is to characterize the modal predicate by appeal to its interaction with the truth predicate. This strategy is put to use by developing the modal theories Modal Friedman-Sheard and Modal Kripke-Feferman. (shrink)

The article explores the tensions of belonging by focusing on the clash between nostalgic and universal values. Because of the inherent tension that they share, the concepts of Bildung and nostalgia provide an opening for understanding human belonging as ranging between nostalgic rootedness and the search for universality. Johann Gottfried Herder’s and Nikolai Frederik Severin Grundtvig’s theories of Bildung, exemplify this clash between nostalgic and universal values. Wilhelm von Humboldt’s thinking offers a theory of Bildung that transcends nostalgic values (...) and points to the world as a place of belonging. In this article I problematize feelings of nostalgia, such as a sense of national belonging, by demonstrating how they might turn into educational values that exclude individuals who do not share the same idea of home and sense of belonging. I employ Agnes Heller’s term ‘value- orientational categories’ to understand how feelings might transform into values. I question and discuss nostalgia’s potential to uphold diversity, given human longing for local versions of home with different languages, cultures, and customs. I then suggest that embracing nostalgia in an educational context can provide a foundation for fostering universal values such as diversity, openness, and flexibility among citizens. Barbara Cassin’s vision of the ‘world freed from belonging’ and her idea of ‘airborne roots’ contribute to this discussion. (shrink)

This paper has two themes. One is the question of how to understand the relation between inner speech and knowledge of one’s own thoughts. My aim here is to probe and challenge the popular neo-Rylean suggestion that we know our own thoughts by ‘overhearing our own silent monologues’, and to sketch an alternative suggestion, inspired by Ryle’s lesser-known discussion of thinking as a ‘serial operation’. The second theme is the question whether, as Ryle apparently thought, we need two different accounts (...) of the epistemology of thinking, corresponding to the distinction between thoughts with respect to which we are active vs passive. I suggest we should be skeptical about the assumption that there is a single distinction here. There are a number of interesting ways in which thinking can involve passivity, but they provide no support for a ‘bifurcationist’ approach to the epistemology of thinking. (shrink)

Der Körper hat Konjunktur. Als ausgestellter, verfüg- und verführbarer begegnet er uns täglichim Übermaß. Es war nur eine Frage der Zeit, bis im Spiel der sich in den Wissenschafteneinander ablösenden turns auch ein corporeal (oder body) turn ausgerufen würde. Dabeibleibt im genannten turn der Gegenstand der Untersuchung nicht selten reduziert auf das, wasman im deutschen Sprachgebrauch »Körper« nennt: ein physisches Substrat, das wie ein Dingunter Dingen beschreibbar ist. Gegen diese Verkürzung stellt der Begri des »Leibes«,spätestens seit Edmund Husserl, eine präzise (...) theoretische Intervention in die wissenschaftlicheund philosophische Diskussion um Körper und Körperlichkeit dar: Dem objektiv beobachtbaren Körper, den wir haben, wird der lebendige Leib, der wir sind, gegenübergestellt. Diesem »Leib«, seiner Geschichte, seinen Varianten und seinem Versprechen gehen dieAutoren der vorliegenden Beiträge nach. Inhaltsübersicht Emmanuel Alloa/Thomas Bedorf/Christian Grüny/Tobias Nikolaus Klass: Einleitung I. Der Leibbegriff in der Phänomenologie Emmanuel Alloa / Natalie Depraz: Edmund Husserl – „Ein merkwürdig unvollkommenkonstituiertes Ding“ – Stefan Kristensen: Maurice Merleau-Ponty I – Körperschema undleibliche Subjektivität – Emmanuel Alloa: Maurice Merleau-Ponty II – Fleisch und Dierenz – David Espinet: Martin Heidegger – Der leibliche Sinn von Sein – Thomas Bedorf: EmmanuelLevinas – Der Leib des Anderen – Karel Novotný: Körper, Leib, Aektivität in Jan Pato č kasPhänomenologie der natürlichen Welt – Julia Scheidegger: Michel Henry – TranszendentaleLeiblichkeit – Jörg Sternagel: Bernhard Waldenfels – Responsivität des Leibes – Kerstin Andermann: Hermann Schmitz – Leiblichkeit als kommunikatives Selbst- und Weltverhältnis II. Zur Geschichte des Leibbegris Emmanuel Alloa: Archaische Leiblichkeit. Die griechische Antike und die Entdeckung desKörpers – Theresia Heimerl: Der Leib Christi und der Körper des Christen: Körper und Leib alszentrale Problemzonen des Christentums – Marc Rölli: Philosophische Anthropologie im 19. Jahrhundert – Zwischen Leib und Körper – Tobias Nikolaus Klass: Friedrich Nietzsche – Denkenam „Leitfaden des Leibes“ – Andreas Cremonini: Sigmund Freud – Der gelebte vs. derphantasmatische Leib – Uta Noppeney: Kurt Goldstein und Frederik Buytendijk – Der Leib-Begri in der organismischen Biologie – Volker Schürmann: Max Scheler und Helmuth Plessner– Leiblichkeit in der Philosophischen Anthropologie – Marion Lauschke: Ernst Cassirer und AbyWarburg – Kulturanthropologie III. Grenzen und Kritik des Leibbegris Christian Grüny: Theodor W. Adorno – Soma und Sensorium – Ulrich Johannes Schneider: Michel Foucault – Der Körper und die Körper – Burkhard Liebsch: Paul Ricoeur – Das leiblicheSelbst begegnet dem Widerstand des Anderen – Mirjam Schaub: Gilles Deleuze – Was weiß ein„Körper ohne Organe“ vom Leib? – Kathrin Busch: Jean-Luc Nancy – Exposition und Berührung– Shaun Gallagher: Embodiment: Leiblichkeit in den Kognitionswissenschaften – Marie-Luise Angerer: Gender und Performance – Ist leibliche Identität ein Konstrukt? – Thomas Bedorf/Selin Gerlek: Praxistheorien – Leibkörperliche Praktiken im Vollzug. (shrink)

This paper is about the status of collective actions. According to one view, collective actions metaphysically reduce to individual actions because sentences about collective actions are merely a shorthand for sentences about individual actions. I reconstruct an argument for this view and show via counterexamples that it is not sound. The argument relies on a paraphrase procedure to unpack alleged shorthand sentences about collective actions into sentences about individual actions. I argue that the best paraphrase procedure that has been put (...) forward so far fails to produce adequate results. (shrink)

ABSTRACT In social evolution theory, biological individuals are often represented on the model of rational agents, that is, as if they were ‘seeking’ to maximize their own reproductive success. In the 1990s, important criticisms of this mode of thinking were made by Brian Skyrms and Elliott Sober, who both argued that ‘rational agent’ models can lead to incorrect predictions when there are positive correlations between individuals’ phenotypes. In this article, I argue that one model of rational choice—namely, Savage’s model —can (...) actually be vindicated in evolutionary biology, provided that the pay-offs are computed in inclusive fitness terms. I also show that the use of this model is better avoided when pay-offs are non-additive, or when certain causal influences affect the outcome of natural selection. The result is a partial rehabilitation of this mode of thinking, conditional on both the additivity of the pay-off structure and the absence of any form of manipulation or coercion. _1_ Introduction _2_ When Natural Selection and Rational Deliberation Part Ways _3_ A Simple Solution: Redefining the Pay-offs in Inclusive Fitness Terms _4_ Sober on Inclusive Fitness Maximization _5_ Inclusive Fitness with Non-additive Pay-offs _6_ Causal Influences and the Savage– Hamilton Model _6.1_ Reciprocity and partner choice _6.2_ Coercion and manipulation _7_ Conclusion Appendix. (shrink)

Kripke’s theory of truth is arguably the most influential approach to self-referential truth and the semantic paradoxes. The use of a partial evaluation scheme is crucial to the theory and the most prominent schemes that are adopted are the strong Kleene and the supervaluation scheme. The strong Kleene scheme is attractive because it ensures the compositionality of the notion of truth. But under the strong Kleene scheme classical tautologies do not, in general, turn out to be true and, as a (...) consequence, classical reasoning is no longer admissible once the notion of truth is involved. The supervaluation scheme adheres to classical reasoning but violates compositionality. Moreover, it turns Kripke’s theory into a rather complicated affair: to check whether a sentence is true we have to look at all admissible precisification of the interpretation of the truth predicate we are presented with. One consequence of this complicated evaluation condition is that under the supervaluation scheme a more proof-theoretic characterization of Kripke’s theory becomes inherently difficult, if not impossible. In this paper we explore the middle ground between the strong Kleene and the supervaluation scheme and provide an evaluation scheme that adheres to classical reasoning but retains many of the attractive features of the strong Kleene scheme. We supplement our semantic investigation with a novel axiomatic theory of truth that matches the semantic theory we have put forth. (shrink)

Digitalisierung wird im vorliegenden Band aus der Theorieperspektive der Philosophischen Anthropologie Plessners betrachtet. Damit geht es im Kern darum, ob und inwieweit sich das Verhältnis von Mensch und Welt im Zeichen von Digitalisierung verändert. Die Verwendung unterschiedlicher Theoriefiguren, Thesen und Themenstellungen aus Plessners Werk erlaubt, die Vielfalt dessen, was mit Digitalisierung verbunden wird, zu systematisieren. Indem mit Plessner der Mensch verstanden wird als exzentrisch positionales Selbst, das Kognitives und Materiales verbindet, steht im Mittelpunkt, wie sich der Mensch eine Welt schafft, (...) die ihn selbst potentiell überformt. Gesellschaft, Autonomie, Technik, Stufen (im plessnerschen Sinne) und schliesslich der Mensch selbst sind die fünf Aspekte, die in den verschiedenen Beiträgen entfaltet werden: Was sind Charakteristika einer digitalen Gesellschaft? Geht die Epoche individueller Freiheit zu Ende? Was bedeutet Digitalisierung für die Autonomie des Menschen? In welches Verhältnis treten Mensch und Technik? Bringt Digitalisierung eine neue Stufe superior des Menschen hervor? Und wo bleibt der Mensch in der Digitalisierung?0. (shrink)

This chapter argues that recent attempts to make sense of the delusion of thought insertion in terms of a distinction between two notions of thought ownership have been unsuccessful. It also proposes an alternative account, in which the delusion is to be interpreted in the light of its prehistory.

It is often assumed that deflationist accounts of truth are a product of philosophy of logic and language in the twentieth century. In this paper I show why this assumption is historically short-sighted. An early version of deflationism about truth can already be found in Brentano’s 1889 lecture “On the Concept of Truth.” That Brentano is a precursor of deflationism has gone largely unnoticed because of a different reception of his lecture: according to most scholars, Brentano proposes in it a (...) revision of the correspondence theory of truth that he later rejected in favour of an epistemic theory. Contrary to this received interpretation, I argue that Brentano actually tried to show how one can minimize an account of truth without thereby sacrificing a robust realist intuition about the objectivity of truth. Brentano held on to this deflationist view in his later years, when he assigned self-evident judgments a primary role in our understanding of truth. (shrink)

This paper provides an overview of the various dual-use concepts applied in national and international non-proliferation and anti-terrorism legislation, such as the Biological and Toxin Weapons Convention, the Chemical Weapons Convention and United Nations Security Council Resolution 1540, and national export control legislation and in relevant codes of conduct. While there is a vast literature covering dual-use concepts in particular with regard to life sciences, this is the first paper that incorporates into such discussion the United Nations Security Council Resolution (...) 1540. In addition, recent developments such as the extension of dual-use export control legislation in the area of human rights protection are also identified and reviewed. The discussion of dual-use concepts is hereby undertaken in the context of human- and/or national-security-based approaches to security. This paper discusses four main concepts of dual use as applied today in international and national law: civilian versus military, peaceful versus non-peaceful, legitimate versus illegitimate and benevolent versus malevolent. In addition, the usage of the term to describe positive technology spin-offs between civilian and military applications is also briefly addressed. Attention is also given to the roles civil society and research ethics may play in the governance of dual-use sciences and technologies. (shrink)

Recent controversy about the use of the vertebrate fossil record for external calibration of molecular clocks centers on two issues, the number of dates used for calibration and the reliability of the fossil calibration date. Viewing matters from a palaeontological perspective, we propose three qualitative, phylogenetic criteria that can be used within a comparative framework for the selection of well-constrained calibration dates from the vertebrate fossil record. On the basis of these criteria, we identify three highly suitable new fossil calibration (...) dates for molecular clock estimates: the lungfish–tetrapod split (between 419 and 408 Ma), the bird–crocodile split (between 251 and 243 Ma), and the alligator–caiman split (between 71 and 66 Ma). Together with our previously suggested bird–lizard split (between 252 and 257 Ma), these four fossil dates span a range of very different ages. They are, in our opinion, more suitable for molecular clock calibration than the traditionally used mammal–bird split, which is less well constrained. We plea for closer interactions between paleontologists and molecular biologists in studying the timescale of vertebrate evolution. BioEssays 27:1069–1075, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

In the strategic document of the African Union approved in 2013 and spanning over 50 years, known as Agenda 2063, we find a blueprint for transforming Africa into a global powerhouse of the future. Many of the themes mentioned in Agenda 2063 are also mentioned in the New Testament, such as slavery, unity, poverty, women, children, discrimination and diversity. It is therefore clear that Christianity has something to contribute to Agenda 2063. Another word used throughout the Agenda 2063 document is (...) ‘transformation’. Concepts such as ‘transformative leadership’ and ‘radical transformation at all levels and in all spheres’ are mentioned. This contribution draws on the Agenda 2063 document to engage the missiological themes of unity, reconciliation and justice through the lens of the Belhar Confession. Deeply aware of the pain and disruption colonial Christianity has caused in many instances in Africa, the author contends that the Good News, particularly the New Testament themes of unity, reconciliation and justice, present a potentially transformative approach towards developing Africa. The research question that this article attends to is: how can the churches in Africa contribute to the aspirations of Agenda 2063 from the themes of unity, justice and reconciliation as declared in the Belhar Confession? By interrogating these key concepts of Agenda 2063 through the Confession of Belhar, the author concludes that the Belhar Confession can be regarded as a key African document, which could be explored further to facilitate unity, reconciliation and justice on the continent.Contribution: This article indicates the important relationship between church and state and the need for a partnership for the benefit of both. The need for a transforming state and a transforming church to participate in a transformed Africa is argued. The article promotes multi-, inter- and transdisciplinary aspects of studies as part of a mission praxis and application. (shrink)

What is the significance of attentiveness in teaching? A spontaneous answer would be that attentiveness is a crucial aspect in the practice of teaching, because if the students do not pay attention...

Han Bertens' The Idea of the Postmodern is the first introductory overview of postmodernism to succeed in providing a witty and accessibile guide to the sometimes befuddling subject. In clear, straight forward, and always elegant prose, Bertens sets out the interdisciplinary aspects, the critical debates, the historical development and the key theorists of postmodernism. He also explains, in thoughtful and illuminating language, the relationship between postmodernism and poststructuralism, lucidly distinguishing modernism from postmodernism through an examination of the fields of architecture, (...) visual arts, and photography. Emphasizing the importance played by heterogeneity and difference in postmodern culture, Bertens carefully and adroitly defines the characteristics of postmodernism at every turn of the page. (shrink)

Kant offered a subtle theory of consciousness and self-knowledge which articulated the intuition that consciousness is a mode of being in a mental state, as opposed to a property of that state. This paper develops this theory and argues that McDowell's treatment of these issues in "Mind" and "World" overlooks the resources of Kant's views. McDowell conflates consciousness and self-consciousness, leading him to formulate too demanding a constraint on rational concept use. Kant's theory can be developed so as to avoid (...) this unfortunate corollary. The paper concludes by comparing Kant's account to contemporary approaches to the problem of consciousness. (shrink)

While the general topic of agency has been collaboratively explored in philosophy and psychology, mental action seems to resist such an interdisciplinary research agenda. Since it is difficult to empirically access mental agency beyond externally measurable behavior, the topic is mainly treated philosophically. However, this has not prevented philosophers from substantiating their arguments with psychological findings, but predominantly with those which allegedly limit the scope and conscious controllability of mental action in favor of automated subpersonal processes. By contrast, the call (...) for a methodological extension through introspective access is particularly noticeable among proponents of a wider significance of mental action. Taking this up, it is shown how an empirical-introspective methodology can obtain a differentiated structure of mental activities occurring in directed thought. The empirical results gained under replicable conditions with 32 participants lead to insights about mental activity regarding (1) immanent causation, (2) content-free intention, (3) active receptivity and (4) its selective openness to mental content, and (5) different levels of observational awareness. These arguments speak for assigning an agentive status to the activities studied and hence for a more significant role of mental action in cognitive processes. (shrink)

The edition presents the recently discovered diaries of Jena Church Historian Karl von Hase's research seminar. Between 1850 and 1883, the reading lists and research agenda of this institution as well as the participants' discussions of current issues in dogmatics and church policy were accurately recorded. The papers enable us to trace in detail how Hase transmitted his liberal views on theology, culture, and politics to students preparing for subsequent academic or ecclesiastical careers. As a result, the historian of higher (...) education can see that in the case of academic theology, the modern seminar went beyond the tasks of methodical historicist research to shape the minds of future academic elites through a close personal relationship with a teacher. (shrink)

Many liberal theories are committed to the promotion of population health, and the principle of non-interference in individual life plans. Public health interventions often bring out a tension between these two values. In this paper, I examine this tension by assessing the justifiability of liberty-restricting policies in the field of obesity prevention. As I want to show, a ‘soft’ form of paternalism, which interferes with people's choices to safeguard their true interests, goes some way in justifying such policies, but it (...) leaves unaddressed the problem of limiting the liberty of those whose true interest is in pursuing an unhealthy lifestyle. I argue that in this latter case, the key to reconcile the promotion of population health with the respect for individual liberty is distributive justice: when we cannot help those who care about their health without doing the same for those who do not, fairness will often require us to do so. (shrink)